MATERIAL SAFETY DATA SHEET
TRETINOIN
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION:
MSDS Name:tretinoin
Synonyms: Vitamin A acid, all-trans-Retinoic acid
Name of Company: WIRUD Co.Ltd
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2. COMPOSITION, INFORMATION ON INGREDIENTS
CAS# : 302-79-4 , Assay 97%
Hazard Symbols: XN
Risk Phrases: 22 38 63
3. HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful if swallowed. Irritating to skin. Possible risk of harm to the unborn child. Light sensitive.
Potential Health Effects
Eye: May cause eye irritation
Skin: Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation: May cause respiratory tract irritation. May be harmful if inhaled.
Chronic: Not available.
4. FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid. Notes to Physician:
5. FIRE FIGHTING MEASURES
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
6. ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
7. HANDLING AND STORAGE
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Do not store in direct sunlight. Store in a tightly closed container. Store in a dry area.
8. EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
9. PHYSICAL AND CHEMICAL PROPERTIES:
Physical State: Crystalline powder
Appearance: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 179.00 - 184.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C20H28O2
Molecular Weight: 300.44
10. STABILITY AND REACTIVITY
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, light.
Incompatibilities with Other Materials: Strong reducing agents. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur.
11. TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 302-79-4: VH6475000
LD50/LC50:
CAS# 302-79-4: Oral, mouse: LD50 = 1100 mg/kg; Oral, rat: LD50 = 2000mg/kg.
Carcinogenicity: all-trans-Retinoic acid - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. See actual entry in RTECS for complete information.
12. ECOLOGICAL INFORMATION:
13. DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
14. TRANSPORT INFORMATION
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
15. REGULATORY INFORMATION
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 38 Irritating to skin.
R 63 Possible risk of harm to the unborn child.
Safety Phrases: S 36/37 Wear suitable protective clothing and gloves.
S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 302-79-4: No information available.
Produced by WIRUD Co.Ltd China