MATERIAL SAFETY DATA SHEET

L-ARGININE BASE

1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND COMPANY INFORMATION

Catalog Number: 100736
Product name: L-ARGININE FREE BASE
Synonyms: 2-Amino-5-Guanidnovaleric Acid

2. COMPOSITION/INFORMATION ON INGREDIENTS

Composition:

3. HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW: May cause irritation to the eyes, skin and respiratory system.
Category of Danger:
Irritant
Principle routes of exposure: Skin
Inhalation: Irritating to respiratory system
Ingestion: Irritating to mouth, throat and stomach
Skin contact: Irritating to skin.
Eye contact: Contact with eyes may cause irritation
ANSI Classification Irritant - eye, skin, respiratory Statements of hazard May Cause Eye, Skin and Respiratory Tract irritation.
Statement of Spill or Leak - ANSI Label Contain and/or absorb spill with inert material (e.g. sand, vermiculite), then place in suitable container. Do not flush to sewer or allow to enter waterways.
Use appropriate Personal Protective Equipment.
Statement of First Aid In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Call a physician.

Precautions - ANSI Label Do not get in eyes, on skin, or on clothing. Wash thoroughly after handling. Avoid breathing vapors. Avoid prolonged or repeated contact with the skin, eyes or respiratory tract. Wash thoroughly after exposure.

4. FIRST AID MEASURES

General advice: In the case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product name: L-ARGININE FREE BASE
Inhalation: Move to fresh air. Call a physician immediately.
Skin contact: Rinse immediately with plenty of water for at least 15 minutes call a physician immediately
Ingestion: Do not induce vomiting without medical advice.
Eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Call a physician immediately Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician
Protection of first-aiders: No information available
Medical conditions aggravated by exposure: None known

5. FIRE FIGHTING MEASURES

Suitable extinguishing media: Use dry chemical, CO2, water spray or "alcohol" foam
Specific hazards: Burning produces irritant fumes.
Unusual hazards: None known special protective equipment for firefighters: Wear self contained breathing apparatus for fire fighting if necessary.
Specific methods: Water mist may be used to cool closed containers.
Flash point: Not determined
Autoignition temperature: Not determined
NFPA rating:
NFPA Health: 1
NFPA Flammability: 1
NFPA Reactivity: 0

6 .ACCIDENTAL RELEASE MEASURES

Personal precautions: Use personal protective equipment.
Environmental precautions: Do not flush into surface water or sanitary sewer system.
Methods for cleaning up: Soak up with inert absorbent material.

7. HANDLING AND STORAGE

Storage:
ROOM TEMPERATURE
Handling: Use only in area provided with appropriate exhaust ventilation.
Safe handling advice: Wear personal protective equipment. Remove and wash contaminated clothing before reuse.
Technical measures/storage conditions: Keep container tightly closed in a dry and well-ventilated place. Keep containers tightly closed in a cool, well ventilated place.
Incompatible products: Oxidising and spontaneously flammable products

8.   EXPOSURE CONTROLS / PERSONAL PROTECTION

Engineering measures: Ensure adequate ventilation.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory protection: Breathing apparatus only if aerosol or dust is formed.
Hand protection: Pvc or other plastic material gloves
Skin and body protection: Impervious clothing
Eye protection: Goggles
Hygiene measures: Handle in accordance with good industrial hygiene and safety practice.

9.PHYSICAL AND CHEMICAL PROPERTIES

Physical state: Powder
Formula: C6H14N4O2
Molecular weight: 174.2
Melting point/range: 222-225°C
Boiling point/range: No Data available at this time.
Density: No data available
Vapor pressure: No data available
Evaporation rate: No data available
Vapor density: No data available
Solubility (in water): Soluble
Flash point: Not determined
Autoignition temperature: Not determined

10.STABILITY AND REACTIVITY

Stability: Stable under recommended storage conditions.
Polymerization: None under normal processing.
Hazardous decomposition products: Nitrogen oxides (NOx)/ammonia/CNMaterials to avoid: Strong oxidising agents
Conditions to avoid: Exposure to air or moisture over prolonged periods.

11. TOXICOLOGICAL INFORMATION

Acute toxicity
Components RTECS Number: Selected LD50s and LC50s
L-ARGININE FREE BASE CF1934200 Not Determined
Chronic toxicity: Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness.
Local effects: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting.

Specific effects: May include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting, headache.
Primary irritation: A primary irritant.
Carcinogenic effects: No data is available on the product itself.

Mutagenic effects: No data is available on the product itself.
Reproductive toxicity: No data is available on the product itself.

12.  ECOLOGICAL INFORMATION

Mobility: No data available
Bioaccumulation: No data available
Ecotoxicity effects: No data available
Aquatic toxicity: May cause long-term adverse effects in the aquatic environment.
Components U.S. DOT - Appendix B -
Marine Pollutan
U.S. DOT - Appendix B-
Severe Marine Pollutants
United Kingdom - The RedmList:
L-ARGININE FREE BASE Not Listed
Ecotoxicity - Fish Species Data
L-ARGININE FREE BASE Not Listed
Components Ecotoxicity - Freshwater Algae Data
Ecotoxicity - Microtox Data Ecotoxicity - Water Flea Data
L-ARGININE FREE BASE Not Listed
Components EPA - ATSDR Priority List EPA - HPV Challenge
Program Chemical List
California - Priority Toxic Pollutants L-ARGININE FREE BASE Not Listed
Components California - Priority Toxic Pollutants California - Priority Toxic Pollutants
L-ARGININE FREE BASE Not Listed

13.  DISPOSAL CONSIDERATIONS

Waste from residues / unused products: Waste disposal must be in accordance with appropriate Federal, State, and local regulations. This product, if unaltered by use, may be disposed of by treatment at a permitted facility or as advised by your local hazardous waste regulatory authority. Residue from fires extinguished with this material may be hazardous. Contaminated packaging: Do not re-use empty containers methods for cleaning up: Soak up with inert absorbent material.

14.  TRANSPORT INFORMATION

UN/Id No: Not regulated
DOT:
Proper shipping name: Not Regulated
Components U.S. DOT - Appendix A Table 1 - Reportable Quantities
L-ARGININE FREE BASE Not Listed
TDG (Canada):
WHMIS hazard class: D2b toxic materials:
IMDG/IMO
IMDG - Hazard Classifications Not Applicable
Components U.S. DOT - Appendix B - Marine Pollutan U.S. DOT - Appendix B - Severe Marine
Pollutants
L-ARGININE FREE BASE Not Listed
IMO-labels:

15.  REGULATORY INFORMATION

International Inventories
L-ARGININE FREE BASE Not Listed
SARA 313 Notification: The above is your notification as to the SARA 313 listing for this product(s) pursuant to Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and 40 CFR Part 372.